[Various hemodynamic indicators in patients with endogenous depression before and during amitriptyline treatment]

The hemodynamic tests using radiocardiographic method, as well as the evaluation of mental status with the help of rating scales was made in 34 patients with endogenous depression. Following differences between depressive patients and age-matched controls were found: higher heart rate (HR), higher systolic arterial pressure (SAP), higher diastolic arterial pressure (DAP), slightly higher systolic index (SI), and higher total peripheral resistance index (TPRI). In addition it was found that HR and TPRI show positive correlation with the intensity of anxiety in Hamilton's++' scale. Two-week lasting amitriptyline treatment partially corrects the unfavourable hemodynamic effects.