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Updated: Mar 8, 2026

Detection of Copy Number Alterations Using Single Cell Sequencing
Published on: February 17, 2017
'COV'COP' allows to detect CNVs responsible for inherited diseases among amplicons sequencing data
P Derouault1, B Parfait2, R Moulinas3
1GEIST, Université de Limoges, Limoges, France.
Summary:
In order to help molecular geneticists to rapidly identify CNVs responsible for inherited diseases among amplicons sequencing data generated by NGS, we designed a user-friendly tool ' Cov'Cop '. Using the run's coverage file provided by the sequencer, Cov'Cop simultaneously analyzes all the patients of the run using a two-stage algorithm containing correction and normalization levels and provides an easily understandable output, showing with various colors, potentially deleted and duplicated amplicons.
Availability And Implementation:
https://git.unilim.fr/merilp02/CovCop.
Contact:
asliabaldini@unilim.fr.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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