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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Mar 8, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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Racial Differences in Selective Laser Trabeculoplasty Efficacy.

Emil Goosen1, Kate Coleman2, Linda Visser3

  • 1Surgeon, Department of Ophthalmology, Port Elizabeth, Eastern Cape South Africa.

Journal of Current Glaucoma Practice
|February 1, 2017
PubMed
Summary

Selective laser trabeculoplasty (SLT) effectively lowered intraocular pressure in South African glaucoma patients. While beneficial for all, Black patients showed more sustained IOP reduction compared to Indian patients.

Keywords:
EthnicityGlaucomaIntraocular pressureSelective laser trabeculoplasty.

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Area of Science:

  • Ophthalmology
  • Laser Therapy
  • Public Health

Background:

  • Sub-Saharan Africa faces a critical shortage of ophthalmologists, with limited basic eye care services.
  • Glaucoma management is challenging due to the scarcity of specialists and patient adherence to medical therapy.
  • Minimally invasive laser treatments like SLT offer a potential solution for widespread glaucoma care.

Purpose of the Study:

  • To evaluate the initial experience and efficacy of selective laser trabeculoplasty (SLT) in a diverse adult glaucoma patient population in Durban, South Africa.
  • To assess the intraocular pressure (IOP) reduction following SLT in patients with and without prior glaucoma treatments.
  • To explore potential racial differences in SLT treatment outcomes.

Main Methods:

  • A 5-year retrospective chart review of adult glaucoma patients who underwent SLT.
  • SLT involved applying 360° treatment with 120-140 closely spaced burns.
  • Intraocular pressure (IOP) changes from baseline were assessed at 1, 3, 6, and 12 months using paired t-tests.

Main Results:

  • SLT resulted in a mean IOP reduction of over 32%, with IOP consistently below 15 mm Hg at all study intervals (p < 0.0001).
  • A 20% IOP reduction was sustained at 12 months in 90% of Black African eyes versus 50% of Indian eyes.
  • The study included 148 eyes from 84 patients, predominantly of African (60) and Indian (21) descent.

Conclusions:

  • Selective laser trabeculoplasty (SLT) is an effective treatment for achieving clinically significant IOP reduction in South African adults with glaucoma.
  • While SLT showed efficacy across racial groups, Black patients experienced more sustained IOP reduction than Indian patients.
  • Implementing SLT as a first-line treatment in Africa is a viable option, especially given challenges with long-term medical therapy adherence.