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Auricular Point Acupressure Therapy: A Safe and Effective Treatment for Postsurgical Abortion Recovery
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Medical treatments for incomplete miscarriage.

Caron Kim1, Sharmani Barnard2, James P Neilson3

  • 1Department of Reproductive Health and Research, WHO, 20 Avenue Appia, Geneva, Switzerland, 1211.

The Cochrane Database of Systematic Reviews
|February 1, 2017
PubMed
Summary

Medical treatment for miscarriage, using misoprostol, and expectant care are viable alternatives to surgery. These miscarriage management options are safe and acceptable, though further research is needed.

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Area of Science:

  • Obstetrics and Gynecology
  • Reproductive Medicine
  • Clinical Trials Research

Background:

  • Miscarriage affects 10-15% of pregnancies.
  • Surgical evacuation of the uterus is a traditional treatment for retained placental tissue.
  • Medical management and expectant care are emerging alternatives.

Purpose of the Study:

  • To evaluate the effectiveness, safety, and acceptability of medical treatments for incomplete miscarriage (before 24 weeks).
  • To compare medical treatments against expectant care and surgical evacuation.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs).
  • Searched Cochrane Pregnancy and Childbirth's Trials Register and reference lists.
  • Included 24 RCTs involving 5577 women; assessed risk of bias and evidence quality (GRADE).

Main Results:

  • Misoprostol vs. expectant care showed no significant difference in complete miscarriage or need for surgery.
  • Misoprostol vs. surgery resulted in slightly lower complete miscarriage rates but significantly fewer surgical evacuations.
  • Medical management led to more unplanned procedures and gastrointestinal side effects (nausea, vomiting, diarrhea) but comparable patient satisfaction.

Conclusions:

  • Medical treatment (misoprostol) and expectant care are acceptable alternatives to surgical evacuation for miscarriage.
  • Availability of health service resources is crucial for supporting all management approaches.
  • Further research, especially for later gestations (>13 weeks), is needed to confirm findings and long-term outcomes.