Related Experiment Video
Updated: Mar 8, 2026
The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
Published on: June 12, 2020
[Treatment of asthenoneurotic disorders in children]
O A Milovanova1, S Yu Astanina2
1Russian Medical Academy of Postgraduate Education, Moscow, Russia; Z.A.Bashlaeva Children's City Clinical Hospital, Moscow, Russia.
Insights
Cogitum effectively improved cognitive functions in children recovering from bacterial meningitis or brain injuries. Eighty percent of patients showed significant gains in accuracy and verbal retention after treatment.
Area of Science:
- Pediatric Neurology
- Neurorehabilitation
Background:
- Asthenoneurotic disorders are common sequelae in children following bacterial meningitis (BM) and brain injury (BI).
- Cognitive deficits can significantly impact a child's quality of life and developmental trajectory.
Purpose of the Study:
- To assess the therapeutic efficacy of cogitum in pediatric patients experiencing asthenoneurotic symptoms post-BM or BI.
- To evaluate the impact of cogitum on cognitive functions and neurological status.
Main Methods:
- A cohort of 24 children (7-12 years) with BM (n=14) or BI (n=10) received cogitum (250-500 mg/day) for 8 weeks.
- Neurological, neuropsychological (Bourdon's, Luria's tests), EEG, and MRI assessments were conducted pre- and post-treatment.
Main Results:
- Significant improvements were observed in 80% of patients in Bourdon's test accuracy (p<0.01) and verbal retention (p<0.001).
- Post-treatment EEG revealed distinct theta, alpha, and beta rhythms with clear zonal differences.
- Clinical observations indicated a broad spectrum of positive effects.
Conclusions:
- Cogitum demonstrates significant efficacy in ameliorating asthenoneurotic disorders and improving cognitive functions in children after BM or BI.
- The drug's positive impact on cognitive performance and neurological markers supports its use in pediatric practice.
Aim:
To evaluate the efficacy of cogitum in the treatment of asthenoneurotic disorders in children after bacterial meningitis (BM) or brain injury (BI).
Material And Methods:
Twenty-four patients were examined. Group 1 included 14 patients with BM, 8 boys and 6 girls, aged 7 - 12 years, mean age 9,91 ± 1,71 years; group 2 consisted of 10 patients with BI, 6 boys and 4 girls, aged 7-12 years, mean age 10,4 ± 2,36 years. All patients received cogitum in dose of 250- 500 mg daily during 8 weeks. Neurological and neuropsychological (Bourdon's test, Luria's tests) examinations, EEG, MRI were performed before and after treatment.
Results And Conclusion:
The study of cognitive functions showed a decrease in the accuracy and speed during performance of Bourdon's and Luria's tests. After the beginning of treatment with cogitum, 80% of the patients in both groups demonstrated a significant improvement in the accuracy of Bourdon's test (р<0,01) and verbal retention (р<0,001). Repeated EEG (3-6 months after treatment) showed the distinct theta- , alpha-, beta- rhythms and clear zonal differences. Given a spectrum of clinical effects of cogitum, the authors recommend it for active use in pediatric practice.
Related Concept Videos
01:22Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
01:26Anxiolytic Drugs: Overview
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic...
01:24Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
01:29Asthma-I: Introduction
01:30Asthma-IV: Nursing Management
First, in...
01:20Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.