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Disturbed integrin expression in the vascular media in CADASIL

Dorota Dziewulska1,2, Ewelina Nycz3

  • 1Department of Neurology, Medical University of Warsaw, Warsaw, Poland. dorota.dziewulska@wum.edu.pl.

Folia Neuropathologica
|February 1, 2017
PubMed
Summary

In cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), integrin β1 subunit expression is decreased in vascular smooth muscle cells. This suggests an early role for integrin β1 in CADASIL pathogenesis.

Keywords:
integrinmicroangiopathytunica mediavascular smooth muscleCADASIL

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