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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Dengue Fever Triggering Kawasaki Disease
Ekta Agarwal1, Dheeraj Shah, Piyush Gupta
1Department of Pediatrics, University College of Medical Sciences, Dilshad Garden, Delhi, India. Correspondence to: Dr Piyush Gupta, Block R6A, Dilshad Garden, Delhi 110 095, India. prof.piyush.gupta@gmail.com.
Persistent fever after dengue may indicate Kawasaki disease. Early diagnosis and treatment with intravenous immunoglobulin are crucial for favorable outcomes in children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Rheumatology
Background:
- Kawasaki disease is a rare but serious condition in children.
- While various infections can trigger Kawasaki disease, dengue fever is an uncommon association.
- Understanding potential triggers is vital for timely diagnosis and management.
Observation:
- A 5-year-old girl presented with fever diagnosed as dengue fever.
- Following initial improvement, her fever persisted beyond the typical dengue duration.
- She met the diagnostic criteria for Kawasaki disease on the seventh day of illness.
Findings:
- The patient received intravenous immunoglobulin therapy.
- The child demonstrated a satisfactory clinical response to the treatment.
- This case highlights a rare co-occurrence of dengue and Kawasaki disease.
Implications:
- Clinicians should consider Kawasaki disease in children with persistent fever after a dengue diagnosis.
- Prompt recognition and treatment of Kawasaki disease are essential to prevent complications.
- This case broadens the differential diagnosis for persistent fever in dengue-endemic regions.
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