[Effect of prednisone on skin tests with allergens]

A double blind study was carried out in 29 patients, 14 were treated with prednisone and 15 with placebo. Prednisone caused significant inhibition of the allergen-induced wheal and flare response, but did not suppress it. The control group, showed a significant rise in the allergen-induced wheal and flare response. The significance of the observed alterations is briefly discussed as well as their probable origin. It is suggested the use of prednisone in allergic patients who need symptomatic treatment, however, we must to think about the possibility for get false-negative results.