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Related Experiment Videos

A Conversation with Kurt and Rochelle Hirschhorn.

Kurt Hirschhorn1, Rochelle Hirschhorn2, Joel N Hirschhorn3,4

  • 1Icahn School of Medicine at Mount Sinai, New York, NY 10029;

Annual Review of Genomics and Human Genetics
|February 2, 2017
PubMed
Summary

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Pioneering geneticists Kurt and Rochelle Hirschhorn discuss the early days of medical genetics and the evolution of genetic counseling. They also share insights on women in science and future directions in human genetics research.

Area of Science:

  • Human Genetics
  • Medical History
  • Bioethics

Background:

  • The interview chronicles the foundational period of medical genetics, highlighting key research and collaborative efforts.
  • It explores the establishment and growth of genetic counseling as a distinct field.
  • The Hirschhorns recount their personal experiences and contributions during this formative era.

Discussion:

  • The discussion addresses the significant challenges faced by women in scientific careers, particularly during the early development of genetics.
  • It examines the ethical considerations and societal impact of advancing human genetics knowledge.
  • The conversation touches upon the interdisciplinary nature of genetics research and its evolution.

Key Insights:

  • The critical role of early pioneers in shaping the field of human genetics and medical genetics.
Keywords:
Pompe diseaseWolf-Hirschhorn syndromeadenosine deaminase deficiencygenetic counselinglymphocyteslysosomal storage disordersmosaicismsomatic reversion

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  • The development of genetic counseling as a vital support system for individuals and families affected by genetic conditions.
  • The persistent need to address gender disparities in science and promote inclusivity.

    • Outlook:

    • Future directions in human genetics research, including advancements in genomic technologies and personalized medicine.
    • The ongoing ethical debates surrounding genetic testing, gene editing, and reproductive technologies.
    • The importance of continued collaboration and interdisciplinary approaches to tackle complex genetic disorders.