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Disorders of the Skeletal Muscle01:28

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
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A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles correspondingly. These complex events are orchestrated by the dynamic cytoskeletal network comprising actin filaments, intermediate filaments, and microtubules. Cytoskeletal crosstalk — the direct and indirect communication between the different components — is crucial for this coordination. Direct communication involves various linker...
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Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
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Dysmobility syndrome: current perspectives.

Keith D Hill1, Kaela Farrier1, Melissa Russell2

  • 1School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University, Perth, WA, Australia.

Clinical Interventions in Aging
|February 2, 2017
PubMed
Summary
This summary is machine-generated.

Dysmability syndrome may help identify older adults at risk of poor health outcomes. This systematic review found it linked to reduced function, falls, fractures, and mortality, highlighting its potential for early intervention.

Keywords:
elderlyfunctional declinemobility

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Area of Science:

  • Gerontology
  • Public Health
  • Clinical Medicine

Background:

  • Dysmability syndrome is a novel concept for identifying older adults prone to adverse health outcomes.
  • Existing research on dysmobility syndrome requires systematic evaluation.

Purpose of the Study:

  • To systematically review the current body of research on dysmobility syndrome.
  • To synthesize findings on the prevalence, associations, and implications of dysmobility syndrome.

Main Methods:

  • A comprehensive systematic review was conducted across multiple major scientific databases (Medline, CINAHL, PubMed, PsycInfo, EMBASE, Scopus).
  • Studies reporting on dysmobility syndrome were identified, and their key characteristics were extracted and summarized.

Main Results:

  • The review identified five relevant studies (3 cross-sectional, 1 case-control, 1 longitudinal); no intervention studies were found.
  • Prevalence estimates for dysmobility syndrome ranged from 22% to 34% in the included studies.
  • Dysmability syndrome was significantly associated with diminished physical function, increased falls and fractures, and mortality.

Conclusions:

  • Dysmability syndrome shows promise as a classification tool for identifying at-risk older adults for timely interventions.
  • Further research is needed to standardize diagnostic criteria, including optimal measures and cut-off points.
  • Investigating the utility of balance performance versus fall history in defining dysmobility syndrome warrants further study.