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Updated: Mar 8, 2026

Robotic Ablation of Atrial Fibrillation
Published on: May 29, 2015
Staged hybrid ablation for persistent and longstanding persistent atrial fibrillation effectively restores sinus
Michal Zembala1, Krzysztof Filipiak1, Oskar Kowalski1
1Department of Cardiac Surgery and Transplantology, Silesian Center For Heart Diseases, Zabrze, Poland.
Insights
Hybrid ablation (HABL) is a safe and effective treatment for persistent atrial fibrillation (AF). This minimally invasive procedure combines epicardial and endocardial ablation, restoring sinus rhythm in most patients after one year.
Area of Science:
- Cardiology
- Electrophysiology
- Minimally Invasive Surgery
Background:
- Persistent (PSAF) and longstanding persistent atrial fibrillation (LSPAF) present therapeutic challenges.
- Hybrid ablation (HABL) integrates endoscopic epicardial and CARTO-guided endocardial ablation.
- HABL aims to overcome limitations of existing AF treatments.
Purpose of the Study:
- To evaluate the safety and feasibility of HABL.
- To assess the effectiveness of HABL in PSAF and LSPAF patients.
- To determine 1-year outcomes of HABL for atrial fibrillation.
Main Methods:
- Prospective, single-center clinical registry study.
- 90 patients with PSAF (n=39) and LSPAF (n=51) underwent HABL.
- Follow-up included 3-, 6-, and 12-month assessments with Holter monitoring.
Main Results:
- 86% of patients achieved sinus rhythm (SR) at 12 months.
- 62.3% were in SR and off antiarrhythmic drugs (AADs) at 1 year.
- Significant reduction in left atrial dimension and increase in left ventricular ejection fraction (LVEF) observed.
Conclusions:
- HABL is a safe and effective treatment option for PSAF and LSPAF.
- Combining epicardial and endocardial ablation restores sinus rhythm.
- Consider HABL for persistent and longstanding persistent atrial fibrillation.
Introduction:
Hybrid ablation (HABL) of atrial fibrillation combining endoscopic, minimally invasive, closed chest epicardial ablation with endocardial CARTO-guided accuracy was introduced to overcome the limitations of current therapeutic options for patients with persistent (PSAF) and longstanding persistent atrial fibrillation (LSPAF). The purpose of this study was to evaluate the procedural safety and feasibility as well as effectiveness of HABL in patients with PSAF and LSPAF 1 year after the procedure.
Material And Methods:
The study is a single-center, prospective clinical registry. From 07/2009 to 12.2014, 90 patients with PSAF (n = 39) and LSPAF (n = 51), at the mean age of 54.8 ±9.8, in mean EHRA class 2.6, underwent HABL. 64.4% of patients had a history of prior cardioversion or catheter ablation. Thirteen patients had LVEF less than 35%. Mean AF duration was 4.5 ±3.7 years. Patients were scheduled for 3-, 6- and 12-month follow-up with 7-day Holter monitoring.
Results:
At 6 months after the procedure 78% (54/69) of patients were in SR. At 12 months after the procedure 86% (59/69) were in SR and 62.3% (43/69) in SR and off class I/III antiarrhythmic drugs (AADs). Only 1% (1/69) of patients required a repeat ablation for atrial flutter. A significant decrease in LA dimension and an increase in LVEF were noted.
Conclusions:
A combination of epicardial and endocardial RF ablation should be considered as a treatment option for patients with persistent and long-standing persistent atrial fibrillation as it is safe and effective in restoring sinus rhythm.
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