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[Trial sequential analysis : Sample size calculation for reliable meta-analyses]

S Weibel1, P Kranke2

  • 1Klinik und Poliklinik für Anästhesiologie, Universitätsklinikum Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Deutschland. Weibel_S@ukw.de.

Der Anaesthesist
|February 2, 2017
PubMed
Summary

Trial Sequential Analysis (TSA) helps reduce random errors in meta-analyses. For breast cancer surgery, TSA indicates regional anesthesia may not significantly reduce pain, unlike initial findings.

Keywords:
Data interpretation, statisticalError sourcesEvidence-based medicineResearch designSample size

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