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The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
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Generation of Human Induced Pluripotent Stem Cell-derived Planar Hair-bearing Skin Organoids Using an Air-Liquid Interface Culture System
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Surface pH of Normal Skin.

A B Gupta, T P Tripathi, B Haldar

    Indian Journal of Dermatology, Venereology and Leprology
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    Summary
    This summary is machine-generated.

    Skin surface pH in Indian adults shows minimal age dependence. Male skin is more acidic than female skin, with significant correlations between forehead and wrist pH levels.

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    Area of Science:

    • Dermatology
    • Human Physiology

    Background:

    • Skin surface pH is a critical factor influencing skin barrier function and health.
    • Understanding variations in skin pH across different demographics and body sites is essential for dermatological research and product development.

    Purpose of the Study:

    • To investigate the skin surface pH in a cohort of Indian individuals.
    • To analyze the influence of age, sex, and body site on skin pH.
    • To determine the correlation between forehead and wrist skin pH.

    Main Methods:

    • Measurement of skin surface pH on the forehead and back of the wrist in 55 Indian individuals (30 males, 25 females) aged 12-58 years.
    • Statistical analysis including t-tests and correlation analysis to evaluate differences and relationships.

    Main Results:

    • No significant dependence of skin surface pH on age was observed.
    • Male skin exhibited a significantly higher acidity (lower pH) compared to female skin.
    • Forehead and wrist pH values did not differ significantly in males, but showed a significant difference in females.
    • Strong positive correlations were found between forehead and wrist skin pH in both sexes (r=0.77 for males, r=0.71 for females).

    Conclusions:

    • Skin surface pH in Indian adults is influenced by sex, with males having more acidic skin.
    • While age is not a significant factor, body site variations exist, particularly in females.
    • Forehead and wrist skin pH are strongly correlated, suggesting regional consistency in skin acidity.