Related Experiment Video

Updated: Mar 8, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

23.7K

Use of Benzathine Pencillin in Impectigo in Children

P K Kar, B H Shah, R C Raval

    Indian Journal of Dermatology, Venereology and Leprology
    |February 2, 2017
    PubMed

    Insights

    Benzathine penicillin injection effectively treated impetigo in children, achieving 92.3% success. Sulfamoxole tablets were less effective, with a 64% success rate in treating this common bacterial skin infection.

    Area of Science:

    • Pediatrics
    • Dermatology
    • Microbiology

    Background:

    • Impetigo is a common bacterial skin infection in children.
    • Staphylococcus aureus and Streptococcus pyogenes are the primary causative agents of impetigo.
    • Understanding the antibiotic susceptibility patterns is crucial for effective treatment.

    Purpose of the Study:

    • To investigate the bacteriology of impetigo in children.
    • To evaluate the efficacy of benzathine penicillin and sulfamoxole in treating impetigo.

    Main Methods:

    • Bacteriological investigation of 150 children with impetigo.
    • Isolation and identification of Staphylococcus aureus and Streptococcus pyogenes.
    • Assessment of antibiotic susceptibility to penicillin.
    • Clinical evaluation of treatment outcomes for benzathine penicillin and sulfamoxole.

    Main Results:

    • Staphylococcus aureus was the predominant organism (92 children), followed by Streptococcus pyogenes (39 children), with 19 children having mixed infections.
    • Penicillin sensitivity was observed in 44% of Staphylococcus aureus and 82% of Streptococcus pyogenes isolates.
    • Benzathine penicillin demonstrated high efficacy (92.3%), regardless of isolate penicillin sensitivity.
    • Sulfamoxole was effective in 64% of cases.

    Conclusions:

    • Benzathine penicillin is a highly effective treatment for childhood impetigo.
    • Empirical treatment with benzathine penicillin can be considered due to its high success rate.
    • Sulfamoxole shows moderate efficacy in treating impetigo.

    More Related Videos

    A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries09:39

    A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

    Published on: December 27, 2016

    18.7K
    Quantifying the Effects of Antimicrobials on In vitro Biofilm Architecture using COMSTAT Software06:18

    Quantifying the Effects of Antimicrobials on In vitro Biofilm Architecture using COMSTAT Software

    Published on: December 14, 2020

    4.4K

    Related Concept Videos

    Acute Pyelonephritis II: Diagnostic Studies and Management01:28

    Acute Pyelonephritis II: Diagnostic Studies and Management

    Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
    568
    Tonsillitis II: Management01:26

    Tonsillitis II: Management

    This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
    499
    Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

    Pharmacokinetics in Pediatric Patients: Drug Excretion

    In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
    343
    Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

    Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

    Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
    583
    Electrophilic Aromatic Substitution: Nitration of Benzene01:20

    Electrophilic Aromatic Substitution: Nitration of Benzene

    The nitration of benzene is an example of an electrophilic aromatic substitution reaction. It involves the formation of a very powerful electrophile, the nitronium ion, which is linear in shape. The reaction occurs through the interaction of two strong acids, sulfuric and nitric acid.
    9.2K
    Rheumatic Heart Disease III: Medical Management01:21

    Rheumatic Heart Disease III: Medical Management

    Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
    436