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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
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Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
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Acrokerato - Elastoidosis Lineaius Manus.

Malkit Singh, A J Kanwar, S C Bharija

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    Summary
    This summary is machine-generated.

    A new variant of acrokerato elastoidosis, acrokerato elastoidosis linearis manus, presents with distinct papules on the fingers of older males. This condition appears unrelated to sun exposure or physical trauma.

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    Area of Science:

    • Dermatology
    • Medical Genetics

    Background:

    • Acrokerato elastoidosis is a rare genodermatosis.
    • Characterized by papules and deformities of the hands and feet.

    Observation:

    • A variant of acrokerato elastoidosis was observed in 55 male patients over 50 years old.
    • The condition manifested as linear, scaly, hyperkeratotic, fissured, and translucent papules on the sides of the thumbs and index fingers.
    • Neither actinic damage nor repeated trauma was evident in the affected individuals.

    Findings:

    • The observed variant is distinct from previously described forms of acrokerato elastoidosis.
    • The clinical presentation suggests a specific phenotype within the spectrum of acrokerato elastoidosis.
    • The etiology does not appear to be linked to environmental factors like sun exposure or trauma.

    Implications:

    • The proposed term 'acrokerato elastoidosis linearis manus' aids in classifying this specific variant.
    • Further research is warranted to understand the genetic and molecular basis of this condition.
    • Accurate diagnosis and classification are crucial for patient management and genetic counseling.