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Updated: Mar 8, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
[Serratia marcescens outbreak in Neonatal Intensive Care Unit: Guayaquil, Ecuador]
Claudia Soria1, Nelson Nieto2, José E Villacís3
1Laboratorio de Bacteriología, Hospital del niño Dr. Francisco de Icaza Bustamante, Guayaquil, Ecuador, csoria@inspi.gob.ec.
Abstract:
We report a Serratia marcescens outbreak occurred in the NICU of a pediatric hospital in Guayaquil, Ecuador. Nine cases of infection were detected, from which septicemia was developed in 55.5%. The index case was a newborn derived from another institution with septic arthritis caused by the outbreak strain. The infection rate was 17.6% and mortality rate was 33.3%. All isolates were resistant to aminoglycosides and susceptible to third generation cephalosporins and carbapenems. Clonality analysis by pulsed-field gel electrophoresis (PFGE) revealed the presence of two closely related clones confirming the horizontal spread. Measures were taken by the committee such as: strengthening the hand hygiene, patient hygiene and cohort studies of gastrointestinal colonization, which allowed the control of the outbreak.
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