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Updated: Mar 8, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
[The use of MALDI-TOF MS for direct identification of bacteria in clinical specimens]
1Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Czech Republic,
Abstract:
MALDI-TOF MS is a method enabling rapid identification of bacteria. This is also important for early initiation of adequate antibiotic therapy in patients with infections. In this review, various methods for direct detection of bacteria in clinical specimens are described. The fundamental part deals with direct identification of bacteria from positive blood cultures. Attention is also paid to identification of bacteria from urine and cerebrospinal fluid. Finally, reliability of the methods is mentioned in comparison with conventional methods.
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