Recent Trends in Endoscopic Bariatric Therapies

Area of Science:

• Medical Science
• Gastroenterology
• Endocrinology

Background:

• Obesity and diabetes mellitus are global health crises with significant economic impact.
• Current treatments like behavioral therapy, medication, and bariatric surgery have limitations in long-term efficacy, safety, and cost.
• Bariatric surgery, while effective, carries risks of morbidity, mortality, and substantial economic burden.

Purpose of the Study:

• To review recent advancements and applications of endoluminal interventions for treating obesity and associated metabolic diseases.
• To highlight the potential of endoscopic techniques as safer and more cost-effective alternatives to conventional bariatric surgery.

Main Methods:

• Review of current literature on endoluminal and transgastric technologies for obesity treatment.
• Discussion of various endoscopic bariatric therapies, including endoscopic gastroplasty, intragastric balloons, endoluminal malabsorptive procedures, and gastric electrical stimulation (GES).

Main Results:

• Endoluminal interventions performed via gastrointestinal flexible endoscopy present promising, safer, and more economical approaches to obesity management.
• Diverse applications of endoluminal techniques are emerging for metabolic obesity disease treatment.
• Gastric electrical stimulation (GES) shows potential for modulating gastric emptying.

Conclusions:

• Endoscopic bariatric therapies represent a rapidly evolving field with significant potential to improve obesity treatment outcomes.
• These minimally invasive techniques offer a viable alternative to traditional surgery, addressing limitations in safety, cost, and long-term effectiveness.
• Continued research and technological development in endoluminal therapies are crucial for advancing metabolic obesity disease management.