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Updated: Mar 8, 2026
Complete Thymectomy in Adult Rats with Non-invasive Endotracheal Intubation
Published on: December 29, 2014
Comparison of Conservative Treatment and Thymectomy on Myasthenia Gravis Outcome
Emanuela Taioli1, Philip Kent Paschal2, Bian Liu1
1Department of Population Health Science, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Policy, Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York; Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, New York.
Background:
A systematic review of the literature was performed to compare long-term outcomes of thymectomy and medical treatment for generalized myasthenia gravis (MG).
Methods:
A Medline search through June 2015 resulted in 71 studies, 27 of which were selected (10,140 patients: 5,275 thymectomies, 4,865 medication).
Results:
The pooled proportion of remission with thymectomy was 0.31 (95% CI, 0.25-0.37), with conservative treatment it was 0.15 (95% CI, 0.12-0.18). The odds ratio (OR) of remission with thymectomy in comparison with medication alone was 2.44 (95% CI, 1.91-3.12) overall and according to medication type and remission definitions.
Conclusions:
Thymectomy is superior to conservative treatment with solely medication on remission in MG.
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