Related Experiment Video
Updated: Mar 8, 2026
Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice
Published on: May 23, 2025
Lipomatous meningioma: A rare subtype of benign metaplastic meningiomas
Mehmet Onur Yüksel1, Mehmet Sabri Gürbüz2, Osman Tanrıverdi1
1Department of Neurosurgery, Erzurum Bolge Training and Research Hospital, Erzurum, Turkey.
Abstract:
Lipomatous meningiomas are extremely rare subtypes of benign meningiomas and are classified as metaplastic meningioma in the World Health Organization classification. We present a 77-year-old man presented with the history of a gradually intensifying headache for the last 3 months. A right frontoparietal mass was detected on his cranial magnetic resonance imaging. The patient was operated on via a right frontoparietal craniotomy, and histopathological diagnosis was lipomatous meningioma. Distinctive characteristics of lipomatous meningiomas were discussed with special emphasis to importance of immunohistochemical examinations, particularly for its differentiation from the tumors showing similar histology though having more aggressive character.
Insights
Lipomatous meningiomas, a rare subtype of benign meningioma, were identified in a 77-year-old man presenting with a headache. Surgical removal and histopathology confirmed the diagnosis, highlighting the need for accurate differentiation from aggressive tumors.
Area of Science:
- Neurosurgery
- Neuropathology
- Oncology
Background:
- Lipomatous meningiomas are rare metaplastic meningiomas, classified by the World Health Organization.
- Benign meningiomas can rarely exhibit lipomatous differentiation.
Observation:
- A 77-year-old male presented with a 3-month history of progressively worsening headaches.
- Cranial magnetic resonance imaging revealed a right frontoparietal mass.
Findings:
- Surgical resection of the frontoparietal mass was performed.
- Histopathological examination confirmed the diagnosis of lipomatous meningioma.
- Immunohistochemical analysis is crucial for distinguishing lipomatous meningiomas from other tumors with similar histology but more aggressive behavior.
Implications:
- This case underscores the rarity of lipomatous meningiomas.
- Accurate histopathological and immunohistochemical diagnosis is vital for appropriate patient management.
- Understanding lipomatous meningioma characteristics aids in differentiating it from more aggressive neoplasms.
