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Updated: Mar 8, 2026

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Published on: January 27, 2010
Effect of Cervical Lidocaine Gel for Pain Relief in Pipelle Endometrial Sampling
Ibrahim Karaca1, Omer Erkan Yapca2, Mehmet Adiyeke3
1Clinic of Obstetrics and Gynecology, Aliağa State Hospital, İzmir, Turkey.
Objective:
To evaluate the efficacy of cervical lidocaine gel in reducing patient discomfort during Pipelle endometrial sampling.
Materials And Methods:
From September 2012 to January 2013, 137 patients were evaluated with Pipelle endometrial biopsy. For group 1 (77 women), 2% lidocaine gel was applied to the cervical canal 3 min before endometrial sampling. For group 2 (60 women), a placebo gel was applied. The pain experienced by the patients during biopsy was evaluated using a 100 mm visual analog scale.
Results:
The pain score was significantly lower during suction curettage (T3) in the group 1 than in the group 2. There was no significant difference between the groups in terms of pain score in other stages of the procedure (2.6±1.3 and 4.5±1.4; p=0.03).
Conclusion:
Cervical 2% lidocaine gel is simple and effective for decreasing pain associated with Pipelle endometrial biopsy.
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