Pediatric Liver Transplantation: Our Experiences

Area of Science:

• Pediatric Hepatology
• Transplantation Surgery
• Gastroenterology

Background:

• Liver transplantation in children is a complex procedure with potential complications.
• Long-term outcomes and complication profiles require continuous evaluation.
• Understanding pediatric liver transplant trends is vital for improving patient care.

Purpose of the Study:

• To assess the outcomes of pediatric liver transplant patients.
• To report on the spectrum of complications encountered post-transplantation.
• To analyze long-term follow-up results in pediatric liver transplant recipients.

Main Methods:

• Retrospective evaluation of pediatric liver transplant patients (0-18 years) from 1997-2016.
• Data collected included age, sex, transplant indications, complications, and follow-up findings.
• Statistical analysis was performed on the collected data.

Main Results:

• 62 pediatric liver transplantations were performed; common indications included Wilson's disease and biliary atresia.
• Post-transplant mortality was 19.6%; acute and chronic rejection rates were 34% and 4.9%.
• Bile leakage (31%) and biliary strictures (11%) were significant complications; 1- and 5-year survival rates were 87% and 84%.

Conclusions:

• Morbidity and mortality rates for pediatric liver transplantation align with published literature.
• The study provides valuable insights into the long-term management of pediatric liver transplant recipients.
• Continuous monitoring and management of complications are essential for favorable outcomes.