Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.0K
T Cell Types and Functions01:24

T Cell Types and Functions

3.0K
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
3.0K
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

5.0K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
5.0K
Autoimmune Disorders01:29

Autoimmune Disorders

2.0K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
2.0K
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

3.2K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
3.2K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Repeated Antigen Exposure on Humoral Tolerance: Antidrug Antibodies After Single-Dose Versus Multi-dose Adalimumab.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy·2026
Same author

Dandruff Is a Low-Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin-17-Producing T Cells, and N-Acyl Ethanolamines.

Immunity, inflammation and disease·2026
Same author

Toward an understanding of neural responses to emotion in recent onset and chronic psoriasis: A feasibility brain imaging study.

JID innovations : skin science from molecules to population health·2026
Same author

Skin care without borders: A United Kingdom-Myanmar teledermatology initiative.

The Journal of investigative dermatology·2026
Same author

A survey of patients attending the Regional Dermatology Training Centre, Moshi, Tanzania, 2017-2020.

The Journal of investigative dermatology·2026
Same author

Evaluation of a Therapeutic Drug Monitoring Strategy for Adalimumab in Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study.

Clinical and translational science·2026
Same journal

Comparative Effectiveness and Safety of Baricitinib and Ritlecitinib in Severe Alopecia Areata: A Real-World Monocentric Retrospective Study.

Dermatology and therapy·2026
Same journal

Matching-Adjusted Indirect Comparison of Risankizumab Versus Icotrokinra in Adult Patients with Moderate-to-Severe Plaque Psoriasis.

Dermatology and therapy·2026
Same journal

Immunobiological Therapy in Moderate-to-Severe Psoriasis: A Retrospective Cohort Study Investigating the Effects of Inadequate Therapeutic Compliance on Drug Survival.

Dermatology and therapy·2026
Same journal

Efficacy and Safety of Rituximab in Pemphigus Foliaceus: A Systematic Review and Meta-analysis.

Dermatology and therapy·2026
Same journal

Modified Delphi Consensus Recommendations for the Management of Psoriasis in Asia-Pacific.

Dermatology and therapy·2026
Same journal

Early Response to Calcipotriol and Betamethasone Dipropionate PAD-Cream at Week 4 in Patients with Mild-to-Moderate Plaque Psoriasis: A Post-Hoc Pooled Analysis of Two Phase III Trials.

Dermatology and therapy·2026
See all related articles

Related Experiment Video

Updated: Mar 8, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.6K

Psoriasis and Atopic Dermatitis.

Christopher E M Griffiths1, Peter van de Kerkhof2, Magdalena Czarnecka-Operacz3

  • 1Dermatology Centre, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK. christopher.griffiths@manchester.ac.uk.

Dermatology and Therapy
|February 3, 2017
PubMed
Summary
This summary is machine-generated.

Psoriasis and atopic dermatitis are chronic inflammatory skin diseases. Individualized treatment is key, but optimal care plans aren't always used in practice.

Keywords:
Atopic dermatitisComorbiditiesDisease burdenEpidemiologyIndividualized treatmentPatient-centered treatmentPsoriasis

More Related Videos

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

976
Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

10.2K

Related Experiment Videos

Last Updated: Mar 8, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.6K
Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

976
Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

10.2K

Area of Science:

  • Dermatology
  • Immunology
  • Public Health

Background:

  • Psoriasis and atopic dermatitis are prevalent chronic inflammatory skin conditions.
  • These diseases present complex challenges including risk factors, incidence, prevalence, and disease burden.
  • Comorbidities significantly increase the clinical importance of both psoriasis and atopic dermatitis.

Purpose of the Study:

  • To review key aspects of psoriasis and atopic dermatitis.
  • To emphasize the importance of individualized, patient-centered treatment strategies.
  • To highlight the gap between theoretical knowledge and clinical practice in managing these conditions.

Main Methods:

  • Literature review and synthesis of current knowledge on psoriasis and atopic dermatitis.
  • Analysis of risk factors, epidemiology, disease burden, and comorbidities.
  • Discussion of current and optimal treatment management strategies.

Main Results:

  • Psoriasis and atopic dermatitis share common features as chronic inflammatory skin diseases.
  • A comprehensive understanding of risk factors, prevalence, and comorbidities is crucial for effective management.
  • Individualized, patient-centered care plans are essential for optimal outcomes.

Conclusions:

  • Despite advancements in understanding optimal care, clinical practice often lags behind theoretical knowledge.
  • There is a need to bridge the gap between evidence-based guidelines and daily patient care for psoriasis and atopic dermatitis.
  • Implementing individualized treatment regimens remains a critical challenge in managing these common skin diseases.