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Related Experiment Video

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A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
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Air-borne Contact Dermatitis in Varanasi.

K K Singh, Gurmohan Singh

    Indian Journal of Dermatology, Venereology and Leprology
    |February 3, 2017
    PubMed
    Summary

    Airborne contact dermatitis affects 13 of 46 patients tested with plant antigens. Parthenium hysterophorus was the most common allergen, highlighting the need for awareness of plant-induced skin reactions.

    Area of Science:

    • Dermatology
    • Allergology
    • Botany

    Background:

    • Airborne contact dermatitis (ACD) is an inflammatory skin condition.
    • Plant-derived allergens are a significant cause of ACD.
    • Identifying specific plant triggers is crucial for patient management.

    Purpose of the Study:

    • To investigate the prevalence of plant-induced airborne contact dermatitis.
    • To identify common plant allergens responsible for ACD in the studied population.

    Main Methods:

    • Patch testing was performed on 46 patients suspected of having ACD.
    • A comprehensive list of 42 plant antigens was used for testing.
    • Patient reactions to each antigen were recorded and analyzed.

    Main Results:

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    • Thirteen out of 46 patients (28.3%) showed sensitivity to one or more plant antigens.
    • Parthenium hysterophorus elicited the highest positive reaction rate (30.0%).
    • Other significant allergens included Amaranthus viridis, Gynandropsis gynandra, and Pennisetum typhoides (all 10.0%).

    Conclusions:

    • Plant antigens are a notable cause of airborne contact dermatitis.
    • Parthenium hysterophorus is a major allergen responsible for ACD in this population.
    • Further research into plant-based ACD is warranted.