Ketoconazole Therapy in Pityriasis Versicolor.

Area of Science:

• Dermatology
• Mycology
• Pharmacology

Background:

• Pityriasis versicolor is a common superficial fungal infection.
• Ketoconazole is an imidazole antifungal agent used to treat fungal infections.

Purpose of the Study:

• To compare the efficacy of 10-day versus 14-day oral ketoconazole courses for treating pityriasis versicolor.
• To assess the safety and recurrence rates associated with these treatment durations.

Main Methods:

• Twenty-six patients diagnosed with pityriasis versicolor were enrolled.
• Treatment involved oral ketoconazole administered for either 10 or 14 consecutive days.

Main Results:

• The 14-day ketoconazole schedule achieved a higher cure rate than the 10-day schedule.
• One patient experienced recurrence of the infection.
• Adverse effects were minimal, with only one case of significant nausea reported.

Conclusions:

• A 14-day course of oral ketoconazole is more effective for pityriasis versicolor than a 10-day course.
• Oral ketoconazole is generally well-tolerated for this indication.
• Longer treatment duration may improve outcomes and reduce recurrence.