Evaluation of Efficacy of Different Topical Corticosteroids

Four different, proprietary preparations of topical cortico-steroids in cream base were evaluated for their relative efficacy on forty adult human volunteers using a modification of the method described by Reddy and Singh. Fluocinolone acetonide 0.025% (Flucort) was rated to be the most efficacious, followed by halcinonide 0.1%, (Halcinonide), beclomethasone dipropionate 0.025% (Beciate) and betamethasone-- valerate 0.12% (Betnovate). However, the differences between these four topical corticosteroids did. not reach the level of statistical significance.