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Articles linked to this work by shared authors, journal, and citation graph.

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Sclerosing Odontogenic Carcinoma: A Review of a Challenging Entity in Malignant Odontogenic Classification With a Focus on Perineural Invasion and Cellular Proliferation.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·2026
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Odontogenic Cysts and Neoplasms.

Elizabeth Ann Bilodeau1, Bobby M Collins2

  • 1Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, G-135 Salk Hall, 3501 Terrace Street, Pittsburgh, PA 15261, USA.

Surgical Pathology Clinics
|February 4, 2017
PubMed
Summary
This summary is machine-generated.

This review covers common and uncommon odontogenic cysts and tumors, detailing their clinical, gross, and microscopic features. It aids in differential diagnosis, prognosis, and avoiding diagnostic pitfalls for various odontogenic lesions.

Keywords:
AmeloblastomaCalcifying epithelial odontogenic tumorClear cell odontogenic carcinomaGnathicKeratocystic odontogenic tumorOdontogenic cystsOdontoma

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Area of Science:

  • Oral pathology
  • Odontogenic neoplasms
  • Cystic lesions of the jaw

Background:

  • Odontogenic cysts and tumors represent a diverse group of jaw lesions.
  • Accurate diagnosis is crucial for appropriate management and patient outcomes.
  • A comprehensive understanding of these entities is essential for clinicians.

Purpose of the Study:

  • To provide a detailed review of common and uncommon odontogenic cysts and tumors.
  • To outline the clinical presentation, gross and microscopic features of these lesions.
  • To discuss differential diagnosis, prognosis, and diagnostic pitfalls.

Main Methods:

  • Review of literature on odontogenic cysts and tumors.
  • Categorization of lesions into inflammatory, developmental, benign, and malignant types.
  • Inclusion of diagnostic criteria and key differentiating features.

Main Results:

  • Detailed descriptions of inflammatory cysts (e.g., periapical cyst), developmental cysts (e.g., dentigerous cyst), benign tumors (e.g., ameloblastoma, odontoma), and malignant tumors (e.g., ameloblastic carcinoma).
  • Emphasis on distinguishing features for differential diagnosis.
  • Highlighting common diagnostic challenges and pitfalls.

Conclusions:

  • Accurate identification of odontogenic cysts and tumors relies on integrating clinical, radiographic, and histopathological findings.
  • Understanding the spectrum of these lesions improves diagnostic accuracy and patient management.
  • This review serves as a valuable resource for pathologists and clinicians managing odontogenic lesions.