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Prolonged neuromuscular block in a preeclamptic patient induced by magnesium sulfate

Mohamed Adnane Berdai1, Smael Labib1, Mustapha Harandou1

  • 1Obstetric and Pediatric Intensive Care Unit, University Hospital Hassan II, Fez, Morocco.

The Pan African Medical Journal
|February 4, 2017
PubMed

Recent large use of magnesium in the obstetric population should incite anesthesiologists to control its side effects and drugs interactions. We report a case of a 30-year-old woman, with severe preeclampsia and HELLP syndrome, receiving sulfate magnesium and nicardipine, who underwent a cesarean section under general anesthesia. She developed a prolonged and deep neuromuscular blockade, which was antagonized three hours later with neostigmine. In case of therapeutic hypermagnesaemia, non-depolarizing relaxants must be used in reduced doses, and at increased time intervals, with appropriate neuromuscular monitoring.

Keywords:
Magnesium sulfateneuromuscular blocknon depolarizing relaxantspregnancy

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