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Nutrition, frailty, and sarcopenia.
Alfonso J Cruz-Jentoft1, Eva Kiesswetter2, Michael Drey2
1Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Ctra.Colmenar km 9,1, 28034, Madrid, Spain. alfonsojose.cruz@salud.madrid.org.
Aging Clinical and Experimental Research
|February 4, 2017
Summary
Malnutrition significantly impacts frailty and sarcopenia, increasing physical dependence risk in older adults. Nutritional interventions show promise in managing these age-related conditions.
Area of Science:
- Geriatrics and nutritional science.
- Focus on age-related physical decline and its management.
Background:
- Frailty and sarcopenia are critical concerns in geriatric care, aiming to prevent physical dependence.
- Definitions are evolving, with significant overlap in physical manifestations.
- Malnutrition, encompassing undernutrition and obesity, is a key factor in their development.
Purpose of the Study:
- To review the role of nutrition, including energy, protein, and other nutrients, in muscle function.
- To explore nutrition's potential as a component of multimodal interventions for frailty and sarcopenia.
Main Methods:
- Literature review focusing on energy and protein intake and their impact on muscle function.
- Discussion of the relationship between diet quality across the lifespan and the incidence of frailty and sarcopenia.
- Reference to the SPRINTT trial for insights into multimodal interventions.
Main Results:
- Malnutrition is central to the pathogenesis of frailty and sarcopenia.
- Dietary quality throughout life is closely linked to the incidence of these conditions.
- Nutritional interventions may reduce or reverse frailty and sarcopenia.
Conclusions:
- Nutrition is a crucial element in addressing frailty and sarcopenia.
- Multimodal strategies incorporating nutritional support are vital for managing these geriatric conditions.
- Further insights are expected from trials like SPRINTT on intervention effectiveness.
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