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Comparison Analysis of Autologous Conditioned Plasma
Radosław Lebiedziński1, Andrzej Borowski1, Marek Synder1
1Department of Orthopaedics and Paediatric Orthopaedics, Medical University in Łódź, Poland.
Ortopedia, Traumatologia, Rehabilitacja
|February 4, 2017
Summary
Proprietary Autologous Conditioned Plasma (ACP) preparation is comparable to commercial kits for platelet concentration. This study found that using hospital equipment can yield effective platelet-rich plasma for orthopaedic applications.
Area of Science:
- Orthopaedic Surgery
- Biomedical Engineering
- Regenerative Medicine
Background:
- Autologous Conditioned Plasma (ACP) offers diverse applications in orthopaedics.
- Evaluating proprietary ACP characteristics is crucial for clinical adoption.
- Comparison with commercial kits aids in understanding preparation variability.
Purpose of the Study:
- To characterize proprietary Autologous Conditioned Plasma (ACP).
- To compare proprietary ACP with ACP produced via a commercial kit.
- To assess the viability of using hospital-based equipment for ACP preparation.
Main Methods:
- ACP samples were prepared using a commercially available kit and disposable hospital equipment.
- Platelet concentration and density were measured in prepared ACP samples.
- Comparisons were made between proprietary ACP and commercial kit preparations.
Main Results:
- Proprietary ACP showed a mean platelet concentration 1.61 times that of peripheral blood.
- Platelet density in proprietary ACP was comparable to commercial preparations (p>0.05).
- Both methods yielded comparable platelet-rich preparations.
Conclusions:
- Disposable hospital equipment can produce effective Autologous Conditioned Plasma (ACP).
- Proprietary ACP preparation is comparable to commercial systems in platelet density.
- This offers a viable alternative for orthopaedic regenerative therapies.
