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Electron microscopy of the influenza virus submembranal structure
R W Ruigrok1, L J Calder, S A Wharton
1Division of Virology, National Institute for Medical Research, London, United Kingdom.
Virology
|November 1, 1989
Abstract:
Electron micrographs of stain-penetrated influenza virus particles show a variety of internal structures that all consist of units of 4 X 4 nm. Isolated influenza virus M-protein, that is reassociated with lipid, forms very similar structures on liposomes. We therefore conclude that the 4 X 4 nm unit is M-protein. We further argue that the M-protein is not arranged with icosahedral symmetry.