Nanomaterials-modified cellulose paper as a platform for biosensing applications.

Area of Science:

• Materials Science
• Analytical Chemistry
• Biomedical Engineering

Background:

• Paper substrates are abundant, portable, and cost-effective materials.
• Functionalizing cellulose paper with nanomaterials enhances its properties for analytical applications.
• Paper-based analytical devices offer advantages for point-of-care (POC) diagnostics.

Purpose of the Study:

• To review recent advances in nanomaterial modification of cellulose paper.
• To describe the properties and fabrication methods for paper-based analytical devices.
• To discuss challenges and future prospects in this field.

Main Methods:

• Review of literature on nanomaterial functionalization of cellulose paper.
• Description of fabrication techniques for diverse nanomaterial modifications.
• Analysis of applications in paper-based analytical devices.

Main Results:

• Diverse nanomaterials (noble metals, metal oxides, carbon nanomaterials, etc.) can functionalize cellulose paper.
• Functionalized paper enables the development of high-performance, low-cost POC devices.
• Various fabrication methods allow for tailored material properties.

Conclusions:

• Nanomaterials-functionalized cellulose paper shows great promise for POC diagnostics.
• Further research is needed to address current challenges and optimize fabrication strategies.
• Mass production of effective POC paper devices is a key future goal.