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When LIN41 Comes to a Fork in the Road, It Takes BOTH Paths: Translational Repression OR mRNA Decay, Depending on the
Jacqelyn M Hand1, Ariel A Bazzini2
1Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Molecular Cell
|February 4, 2017
Abstract:
In this issue, Aeschimann et al. (2017) demonstrate that, depending on the target location site (5'UTR or 3'UTR), LIN41 triggers repression of translation or mRNA decay, suggesting that one factor may use two independent pathways of post-transcriptional gene regulation.
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