Related Experiment Video
Updated: Oct 13, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[5 years' infection statistics of an orthopedic clinic--pathogen spectrum, resistance status, therapeutic
1Orthop. Klinik Volmarstein, Wetter.
Abstract:
In 1983 we started our statistical control for postoperative infections. The data are checked every half year. Most common bacteria was Staph. aureus followed by Staph. epidermidis. We found a difference in the spectrum of bacteria between our postop. patients and the referred cases. A surgeon related control and our new operating theatres reduced the infection rate from 2.2% to 0.8%. For our total joint replacements we additionally used perioperative antibiotics. The change in the antibiotic from Cefoxitine to Cefacedone reduced the infection rate from 4.7% to 0.8%. The permanent control of bacteria and of their resistance to antibiotics allows us to reduce the number of drugs used and to simplify treatment without loosing efficiency of therapy. This is--in a double sense--a good way for reducing costs.
Related Concept Videos
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Mechanism of Antibiotic Resistance in MRSA
Clinical Significance of Antibiotic Resistance

