[Glioblastoma, innovations in surgery]
Related Experiment Video
Updated: Mar 8, 2026

07:25
Author Spotlight: Multimodal Imaging Strategies for Optimizing Drug Delivery and Early Detection in Glioblastoma Treatment
Published on: March 1, 2024
3.1K
Thiebaud Picart1, Jacques Guyotat1
1Service de neurochirurgie oncologique et vasculaire, hôpital neurologique Pierre Wertheimer, CHU de Lyon, 59 Boulevard Pinel, 69500 Bron, France.
Abstract:
One of the innovative principles in glioblastoma surgery consists in making the tumour fluorescent in order for it to be more easily visualised during the procedure. 5-aminolevulinic acid (5-ALA) undergoes an enzyme transformation, turning into another molecule, protoporphyrine IX (PPIX) whose property is fluorescence. It emits red light when it is stimulated by blue light.

