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Updated: Aug 23, 2026
Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
Published on: September 14, 2009
Relationship between yellow plaque grade and tissue protrusion after stent implantation: A coronary angioscopy study
Toru Miyoshi1, Hideo Kawakami1, Fumiyasu Seike1
1Department of Cardiovascular Medicine, Ehime Prefectural Imabari Hospital, Imabari, Japan.
Background:
Tissue protrusion detected with optical coherence tomography after percutaneous coronary intervention using stents is one of the risk factors for early stent thrombosis. However, tissue protrusion features have not been described. The aim of this study was to compare tissue morphology at stented sites with or without tissue protrusion by using coronary angioscopy.
Methods:
Using optical coherence tomography and coronary angioscopy, we assessed 42 patients [31 men, 11 women; age, 70.7±7.4years; acute coronary syndrome (ACS), n=19; effort angina pectoris (EAP), n=23] after stenting.
Results:
Twenty patients had tissue protrusion. ACS patients had a higher incidence of tissue protrusion than EAP patients (70.0% vs 29.4%; p=0.002). The plaque at the protrusion site had higher-grade yellow plaque with thrombus than those without protrusion (2.35±0.67 vs 1.40±0.67; p<0.001). The plaque at protrusion sites developed more thrombi (60.0% vs 22.7%; p=0.041).
Conclusions:
Tissue protrusion after stent implantation was associated with high-grade yellow plaque with thrombi.
