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Updated: Mar 8, 2026
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Infection of Zebrafish Embryos with Intracellular Bacterial Pathogens
Published on: March 15, 2012
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Live-cell imaging of Salmonella Typhimurium interaction with zebrafish larvae after injection and immersion delivery
Macarena Varas1, Alonso Fariña1, Francisco Díaz-Pascual1
1Laboratorio de Microbiología de Sistemas, Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Chile.
Journal of Microbiological Methods
|February 6, 2017
Abstract:
The zebrafish model has been used to determine the role of vertebrate innate immunity during bacterial infections. Here, we compare the in vivo immune response induced by GFP-tagged Salmonella Typhimurium inoculated by immersion and microinjection in transgenic zebrafish larvae. Our novel infection protocols in zebrafish allow live-cell imaging of Salmonella colonization.
