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Gastrojejunostomy tube complications - A single center experience and systematic review
James Morse1, Robert Baird1, Karl Muchantef2
1Divisions of Pediatric General and Thoracic Surgery, The Montreal Children's Hospital of the McGill University Health Centre, Montreal, Quebec, Canada.
Insights
Gastrojejunostomy tubes (GJTs) are linked to serious complications, especially in infants under 10kg. These tubes require frequent revisions, and perforation risk is significantly higher in smaller children.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Medical Devices
Background:
- Gastrojejunostomy tubes (GJTs) are crucial for enteral nutrition in pediatric patients with feeding intolerance.
- Complications associated with GJTs may be more prevalent in younger and smaller infants.
Purpose of the Study:
- To evaluate the complication rate of gastrojejunostomy tube (GJT) placements at a single institution.
- To systematically review existing literature on GJT complications, focusing on perforation and mortality rates.
Main Methods:
- Retrospective analysis of GJT placements from 2009-2015 at a single institution.
- Systematic literature review following MOOSE guidelines, assessing 48 articles on 2726 procedures.
Main Results:
- At the institution, 48 children underwent 154 successful GJT insertions, primarily for reflux and aspiration.
- Systematic review estimated an overall GJT perforation rate of 2.1%, with significantly higher rates in children <10kg (3.1%) versus ≥10kg (0.1%).
- Overall mortality was estimated at 0.9%, with most perforations occurring within 30 days of placement.
Conclusions:
- Gastrojejunostomy tubes are associated with substantial complications and often necessitate revision or replacement.
- GJT insertion in pediatric patients weighing less than 10kg carries an elevated risk of perforation, warranting caution.
Purpose:
Gastrojejunostomy tubes (GJTs) enable enteral nutrition in infants/children with feeding intolerance. However, complications may be increased in small infants. We evaluated our single-institution GJT complication rate and systematically reviewed existing literature.
Methods:
With REB approval, a retrospective single-institution analysis of GJT placements between 2009 and 2015 was performed. For the systematic review, MOOSE guidelines were followed.
Results:
At our institution, 48 children underwent 154/159 successful insertions primarily for gastroesophageal reflux (n=27; 55%) and aspiration (n=11; 23%). Median age at first GJT insertion was 2.2years (0.2-18). Thirty-five (73%) had an index insertion when ≤10kg. GJTs caused 2 perforations and 1 death. The systematic review assessed 48 articles representing 2726 procedures. Overall perforation rate was estimated as 2.1% (n=36 studies, 23/1092, 95% CI: 1.0-3.2). Perforation rates in children <10kg versus ≥10kg were estimated as 3.1%/procedure (95% CI: 1.1%-5.0%) and 0.1%/procedure (95% CI: 0%-0.3%), respectively. The relative risk of perforation was 9.4 (95% CI: 2.8-31.3). Overall mortality was estimated as 0.9%/patient (n=39 studies; 95% CI: 0.2-1.6%). Most perforations (19/23; 83%) occurred ≤30days of attempted tube placement.
Conclusion:
Gastrojejunostomy tubes are associated with significant complications and frequently require revision/replacement. Insertion in patients <10kg is associated with increased perforation risk. Caution is warranted in this subgroup.
Level Of Evidence:
Level II.
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