Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Relationship between central visual field and pattern VECP in optic neuritis].

N Fujimoto, E Adachi-Usami

    Nippon Ganka Gakkai Zasshi
    |June 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A single-centre analysis of the clinical characteristics of non-tuberculous mycobacterial lung disease caused by rare species.

    IJTLD open·2026
    Same author

    CHANGES IN ACTIVITIES OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE IN SEA URCHIN EGGS AFTER FERTILIZATION.

    Development, growth & differentiation·2023
    Same author

    First-line nivolumab plus ipilimumab versus chemotherapy in patients with unresectable malignant pleural mesothelioma: 3-year outcomes from CheckMate 743.

    Annals of oncology : official journal of the European Society for Medical Oncology·2022
    Same author

    Anti-PD-1 antibody monotherapy versus anti-PD-1 plus anti-CTLA-4 combination therapy as first-line immunotherapy in unresectable or metastatic mucosal melanoma: a retrospective, multicenter study of 329 Japanese cases (JMAC study).

    ESMO open·2021
    Same author

    Culture substrates made of elastomeric micro-tripod arrays for long-term expansion of human pluripotent stem cells.

    Journal of materials chemistry. B·2020
    Same author

    Sézary syndrome involving the intestinal tract.

    Clinical and experimental dermatology·2019

    Optic neuritis affecting the visual field within 10 degrees correlates significantly with delayed P100 peak latency in pattern visually evoked cortical potentials (PVECPs). Abnormal visual fields and prolonged PVECPs latency were observed in multiple sclerosis and unknown cause cases.

    Area of Science:

    • Ophthalmology
    • Neuroscience
    • Clinical Electrophysiology

    Background:

    • Optic neuritis is an inflammatory condition affecting the optic nerve, potentially leading to vision loss.
    • Pattern visually evoked cortical potentials (PVECPs) and visual field testing are crucial diagnostic tools for assessing optic nerve function.

    Purpose of the Study:

    • To investigate the correlation between central visual field defects and PVECPs abnormalities in patients with optic neuritis.
    • To evaluate the relationship between PVECPs latency and amplitude with visual field parameters in optic neuritis.

    Main Methods:

    • Compared visual field data (within 10 degrees) with P100 latency and amplitude of PVECPs in 25 eyes with MS-related optic neuritis and 21 eyes with unknown etiology.
    • Utilized automated perimetry (Octopus program 31) and a television system for PVECPs recording.

    Related Experiment Videos

  • Defined abnormalities based on established criteria for visual field defects and P100 latency.

    • Main Results:

    • A significant correlation was found between 10-degree visual field abnormalities and prolonged PVECPs latency in both MS and unknown cause groups.
    • Eyes with a mean visual field loss over 4dB within 10 degrees consistently showed delayed P100 latency.
    • Reduced PVECPs amplitude (up to 61%) was observed in affected eyes with abnormal visual fields and delayed latency compared to fellow eyes.

    Conclusions:

    • PVECPs latency is a reliable indicator of visual field deficits in the central 10 degrees for optic neuritis patients.
    • The severity of vision loss and visual field impairment in optic neuritis tends to correlate with prolonged P100 latency.
    • PVECPs amplitude reduction may indicate significant optic nerve damage in optic neuritis.