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Physapubescin, a natural withanolide as a kidney-type glutaminase (KGA) inhibitor

Li Cheng1, Can-Rong Wu2, Li-Han Zhu3

  • 1Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China; School of Traditional Chinese Materia Medica, Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.

Bioorganic & Medicinal Chemistry Letters
|February 9, 2017
PubMed

Keywords:
CytotoxicityEnzyme inhibitionKGA inhibitorPhysapubescinStructure-based virtual ligand screening

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