Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aortic Regurgitation III: Medical Management

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Association of EVITA with safety in advanced urothelial carcinoma: A multicenter real-world study.

Urologic oncology·2026

Same author

Real-world Outcomes of Adjuvant Nivolumab in High-risk Bladder and Upper Tract Urothelial Carcinoma after Radical Surgery.

European urology open science·2026

Same author

Testosterone treatment for micropenis in partial androgen insensitivity syndrome.

JCEM case reports·2026

Same author

Presenting postoperative mortality as percentages and natural frequencies (1-in-N) in major urologic cancer surgeries.

Urologic oncology·2026

Same author

Efficient Gene Expression System in Medaka Embryos Enables Functional Characterization of nt5c1a Paralogs Involved in Inosine Monophosphate Metabolism.

Genesis (New York, N.Y. : 2000)·2026

Same author

Complete genome analysis of <i>Edwardsiella tarda</i> strain MYK24826 isolated from a Japanese patient with prosthetic valve endocarditis.

Microbiology resource announcements·2026

Search research articles

Related Experiment Video

Updated: Mar 7, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

[L-shaped Partial Upper Sternotomy Approach for Aortic Valve Replacement].

Hiroshi Munakata¹, Noriko Oyama, Yu Murakami

¹Department of Cardiovascular Surgery, Okinawa Prefectural Nambu Medical Center and Children's Medical Center, Okinawa, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery

|February 9, 2017

Summary

This summary is machine-generated.

Minimally invasive aortic valve replacement (MICS-AVR) using an L-shaped sternotomy showed no operative mortality in 16 patients. Further clinical experience is needed to confirm its benefits over conventional sternotomy for aortic stenosis treatment.

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Related Experiment Videos

Last Updated: Mar 7, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Area of Science:

Cardiovascular Surgery
Minimally Invasive Cardiac Surgery

Background:

Severe aortic stenosis necessitates aortic valve replacement.
Minimally invasive aortic valve replacement (MICS-AVR) may offer reduced postoperative discomfort and faster recovery.
L-shaped MICS-AVR, an upper partial sternotomy, is a common MICS-AVR approach.

Purpose of the Study:

To evaluate the safety and efficacy of L-shaped MICS-AVR.
To compare L-shaped MICS-AVR with conventional sternotomy AVR (C-AVR), particularly in an over-octogenarian subgroup.

Main Methods:

Retrospective analysis of 16 patients undergoing L-shaped MICS-AVR since October 2013.
Comparison of an over-octogenarian subgroup (n=7) with patients undergoing C-AVR (n=10) during the same period.

Main Results:

No operative mortality or major complications (bleeding, infection, leakage, pulmonary issues) in the L-shaped MICS-AVR group.
A trend towards a better postoperative course in L-shaped MICS-AVR compared to C-AVR, though not statistically significant.
Significantly longer cardiopulmonary bypass and cross-clamp times in L-shaped MICS-AVR compared to C-AVR.

Conclusions:

L-shaped MICS-AVR appears safe with no operative mortality or major complications in this initial series.
More clinical experience and improved preoperative imaging are needed to fully elucidate the benefits of L-shaped MICS-AVR.
Future advancements may involve novel devices combined with L-shaped MICS-AVR for improved outcomes.