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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Related Experiment Video

Updated: Mar 7, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
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Onychomycosis in an Infant.

V Ramesh, B S N Reddy

    Indian Journal of Dermatology, Venereology and Leprology
    |February 9, 2017
    PubMed
    Summary

    A rare case of distal subungual onychomycosis, a fungal nail infection caused by Trichophyton rubrum, is reported in a three-month-old infant. This represents the youngest documented patient with this condition in English medical literature.

    Area of Science:

    • Dermatology
    • Mycology
    • Pediatrics

    Background:

    • Onychomycosis is a common fungal infection affecting the nails.
    • Distal subungual onychomycosis is the most prevalent clinical form.
    • While typically seen in adults, pediatric cases are less common.

    Observation:

    • A three-month-old infant presented with symptoms suggestive of distal subungual onychomycosis.
    • The causative agent was identified as Trichophyton rubrum.
    • The infant had no significant underlying health conditions.

    Findings:

    • This case represents the youngest patient diagnosed with distal subungual onychomycosis to date in the English literature.
    • The successful identification of Trichophyton rubrum in such a young patient highlights the pathogen's potential to infect even neonates.

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  • The clinical presentation in this infant underscores the need for considering onychomycosis in the differential diagnosis of nail abnormalities in early infancy.
  • Implications:

    • Early diagnosis and treatment of pediatric onychomycosis are crucial to prevent potential complications and transmission.
    • This case broadens the known age spectrum for distal subungual onychomycosis.
    • Further research into the risk factors and management strategies for onychomycosis in infants is warranted.