Related Experiment Video

Updated: Mar 7, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

12.0K

Effect of bronchopulmonary dysplasia on early intellectual development in preterm infants

Fatao Lin1, Haipeng Dong2, Yanyan Song1

  • 1Department of Neonatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

Pediatrics International : Official Journal of the Japan Pediatric Society
|February 9, 2017
PubMed

Insights

Bronchopulmonary dysplasia (BPD) significantly impacts preterm infants' early intellectual development. Close monitoring of the nervous system is crucial for these vulnerable infants to address developmental delays.

Area of Science:

  • Neonatal Development
  • Pediatric Neurology
  • Respiratory Medicine

Background:

  • Bronchopulmonary dysplasia (BPD) is a chronic lung disease affecting preterm infants.
  • Preterm infants are at higher risk for neurodevelopmental challenges.
  • The impact of BPD on early intellectual development requires further investigation.

Purpose of the Study:

  • To investigate the effect of bronchopulmonary dysplasia (BPD) on the early intellectual development of preterm infants.
  • To compare neurodevelopmental outcomes between preterm infants with and without BPD, and healthy term infants.

Main Methods:

  • Recruited 83 preterm infants with BPD, 89 preterm infants without BPD, and 98 healthy term infants.
  • Evaluated neural and intellectual development using the Gesell Development Scale at multiple time points.
  • Utilized multivariate logistic regression to identify associations between BPD and neurological outcomes.

Main Results:

  • Preterm infants showed lower developmental quotients compared to term infants across multiple skill domains.
  • Preterm infants with BPD exhibited more frequent neurodevelopmental deficits than those without BPD.
  • BPD was independently associated with adverse neurological outcomes at 9-12 months adjusted age.

Conclusions:

  • Early intelligence disturbances are significantly more common in infants with BPD.
  • Enhanced monitoring of nervous system development is recommended for infants with BPD.
Abstract

Keywords:
bronchopulmonary dysplasiafollow upintellectual developmentpreterm infant

More Related Videos

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

741
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

88.2K

Related Concept Videos

Intellectual Disability01:29

Intellectual Disability

Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
940
Environmental Influences on Intelligence01:29

Environmental Influences on Intelligence

Despite the strong genetic influence on traits like intelligence, environmental factors significantly shape outcomes. For example, while over 90% of height variation is due to genetic differences, environmental factors such as nutrition also have a notable impact. Similarly, for intelligence, changes in a child's surroundings can significantly alter their IQ. Research shows that enriched environments boost children's academic success and help them develop key cognitive skills. Children...
1.0K
Biological Influences on Intelligence01:30

Biological Influences on Intelligence

Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter...
623
The Nativist Approach01:21

The Nativist Approach

The nativist approach to infant cognitive development proposes that infants are born with inherent knowledge structures that allow them to interpret the world almost immediately. This perspective contrasts with earlier developmental theories, such as those proposed by Jean Piaget, which emphasized a more gradual acquisition of cognitive abilities through interaction with the environment. One key concept in this approach is object permanence — the understanding that objects continue to...
533
Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
684
Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
1.0K