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In Vitro Generation of Somite Derivatives from Human Induced Pluripotent Stem Cells
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In Vivo Human Somitogenesis Guides Somite Development from hPSCs

Haibin Xi1, Wakana Fujiwara2, Karen Gonzalez3

  • 1Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Center for Duchenne Muscular Dystrophy, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Cell Reports
|February 9, 2017
PubMed
Summary

Researchers identified key signaling pathways regulating human somitogenesis, developing a method to create somite cells from pluripotent stem cells. These cells can differentiate into various tissues, aiding disease treatment research.

Keywords:
chondrogenesisdevelopmentdifferentiationhuman pluripotent stem cellsosteogenesisskeletal myogenesissomite

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