Antimicrobial activity of N,N'-dialkylpolymethylenediamines against some dental plaque bacteria

Twenty N,N'-dialkylpolymethylendiamine derivatives were synthesized, and a study was made of their antimicrobial activities in vitro against four oral microorganisms which are related to dental caries. The maximum activity was shown by N,N'-dinonyl or N,N'-didecyl derivatives among the complete homologous series of compounds studied.