Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

61.6K
Overview
61.6K
Combined Effects of Drugs: Synergism01:27

Combined Effects of Drugs: Synergism

7.1K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
7.1K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

1.7K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.7K
Antimicrobial Proteins01:23

Antimicrobial Proteins

14.9K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
14.9K
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

1.6K
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
1.6K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.2K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Equal opportunities in access to medical rehabilitation].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
Same author

Intersectional inequalities in self-rated health in Germany across sex/gender, migration, education and income: a cross-sectional study.

Journal of epidemiology and community health·2026
Same author

Gender and mental health of adolescents: A conceptual framework developed in a Delphi study.

PloS one·2025
Same author

[Laudation on the Occasion of the Presentation of the Salomon Neumann Medal 2025 to Professor Dr. Theda Borde].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2025
Same author

Racism in public health authorities-A scoping review and situational analysis.

PLOS global public health·2025
Same author

[Laudation on the Occasion of the Presentation of the Salomon Neumann Medal 2025 to Professor Dr. Theda Borde].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2025

Related Experiment Video

Updated: Mar 7, 2026

Antibiotic Dereplication Using the Antibiotic Resistance Platform
10:49

Antibiotic Dereplication Using the Antibiotic Resistance Platform

Published on: October 17, 2019

11.8K

[Antibiotics - In Which Fields is there Need for Action?]

Hendrik Sauskojus1, Christian Wagner-Ahlfs2, Oliver Razum3

  • 1BUKO Pharma-Kampagne, Bielefeld.

Gesundheitswesen (Bundesverband Der Arzte Des Offentlichen Gesundheitsdienstes (Germany))
|February 9, 2017
PubMed
Summary

Antibiotic resistance is a growing problem where bacteria evolve to resist drugs, making infections harder to treat. Urgent, targeted actions are needed to preserve antibiotic effectiveness for the future.

More Related Videos

Stress-induced Antibiotic Susceptibility Testing on a Chip
12:41

Stress-induced Antibiotic Susceptibility Testing on a Chip

Published on: January 8, 2014

7.0K
A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

9.4K

Related Experiment Videos

Last Updated: Mar 7, 2026

Antibiotic Dereplication Using the Antibiotic Resistance Platform
10:49

Antibiotic Dereplication Using the Antibiotic Resistance Platform

Published on: October 17, 2019

11.8K
Stress-induced Antibiotic Susceptibility Testing on a Chip
12:41

Stress-induced Antibiotic Susceptibility Testing on a Chip

Published on: January 8, 2014

7.0K
A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

9.4K

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Antibiotics have been crucial for treating bacterial infections for decades.
  • Natural bacterial evolution of resistance mechanisms is accelerated by increased global antibiotic use.
  • This has led to difficulties in treating diseases like tuberculosis and gonorrhea, and increased healthcare-associated infections.

Purpose of the Study:

  • To highlight the escalating issue of antibiotic resistance.
  • To emphasize the inadequacy of current action plans.
  • To advocate for targeted interventions to maintain antibiotic efficacy.

Main Methods:

  • This study is a review of the current state of antibiotic resistance.
  • It synthesizes information on the causes and consequences of resistance.
  • It discusses the limitations of existing strategies.

Main Results:

  • Bacterial resistance to antibiotics is increasing globally.
  • Existing countermeasures are often insufficient or not fully implemented.
  • The effectiveness of antibiotics as a treatment option is under significant threat.

Conclusions:

  • Antibiotic resistance poses a severe threat to global health.
  • A multifaceted and targeted approach is essential to combat this challenge.
  • Continued efforts are required to ensure antibiotics remain viable for treating infections.