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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

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Prevalence and determinants of left ventricular geometric abnormalities in hypertensive patients: A study based on

Tao Sha1, Yu-Qing Huang2, An-Ping Cai2

  • 1Southern Medical University, Guangzhou 510515, Guangdong, China; Department of Cardiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Cardiovascular Institute, Guangzhou, 510100, Guangdong, China.

Hellenic Journal of Cardiology : HJC = Hellenike Kardiologike Epitheorese
|February 10, 2017
PubMed

Insights

Hypertension can cause left ventricular (LV) geometric abnormalities, with concentric remodeling being most common. Risk factors like large waist and neck circumference are linked to concentric abnormalities, while BMI and SBP are inversely associated.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Echocardiography

Background:

  • Left ventricular (LV) geometric abnormalities are common in hypertensive patients.
  • Understanding the specific risk factors associated with different types of LV geometric abnormalities is crucial for targeted interventions.

Purpose of the Study:

  • To investigate the association between various risk factors and distinct types of left ventricular (LV) geometric abnormalities in hypertensive individuals.
  • To identify differential risk profiles for concentric remodeling, eccentric dilated LVH, and concentric LVH.

Main Methods:

  • Retrospective analysis of 2290 hypertensive participants with preserved ejection fraction (≥50%) and no other cardiovascular or valve disease.
  • Classification of LV geometric abnormalities based on a new system.
  • Statistical analysis to determine associations between risk factors (e.g., BMI, SBP, WC, NC, age, gender, alcohol use, hyperuricemia) and LV geometric patterns.

Main Results:

  • LV geometric abnormalities were prevalent in 64.6% of participants.
  • Concentric LV remodeling was the most common abnormality (40.3%).
  • Large waist circumference (WC) and neck circumference (NC) were associated with concentric remodeling. Body mass index (BMI) and systolic blood pressure (SBP) showed inverse associations.
  • SBP and age were linked to eccentric dilated LVH, while male gender was inversely associated. Age was the strongest risk factor for eccentric dilated LVH.
  • Age, NC, SBP, hyperuricemia, and alcohol use were positively associated with concentric LVH. BMI and male gender were negatively associated.

Conclusions:

  • The prevalence of hypertensive LV geometric abnormality is notably high in rural Southern China.
  • Concentric LV geometric abnormalities are associated with a broader range of risk factors compared to eccentric abnormalities.
  • Risk factors for concentric abnormalities include large WC and NC, age, SBP, hyperuricemia, alcohol use, BMI, and gender.
Abstract

Keywords:
Cardiovascular risk factorHypertensionLV remodelingLeft ventricular geometric abnormality

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