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Paracetamol suppositories: a comparative study
1Children's Research Centre, Our Lady's Hospital for Sick Children, Dublin.
Archives of Disease in Childhood
|October 1, 1989
Abstract:
Paracetamol suppositories in two different bases were given to children who had fever after operations. Plasma concentrations and the effect on temperature were compared. There was a significant correlation between peak plasma concentrations and maximum drop in temperature. A lipophilic base produced better results than a hydrophilic base.