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Quality of life after tonsillectomy versus azithromycin
Diaa El Din Mohamed El Hennawi1, Mohamed Rifaat Ahmed1
1Otolaryngology Unit, Faculty of Medicine, Suez Canal University , Ismailia, Egypt.
Interventional Medicine & Applied Science
|February 10, 2017
Summary
Azithromycin effectively prevents recurrent tonsillitis and improves children's quality of life (QOL), offering similar outcomes to tonsillectomy without surgery. This treatment benefits families by reducing the burden of recurrent tonsillitis.
Area of Science:
- Pediatric Otolaryngology
- Infectious Diseases
- Quality of Life Research
Background:
- Recurrent tonsillitis significantly impacts children's quality of life (QOL) and family well-being.
- Conventional dissection tonsillectomy is a common treatment for recurrent tonsillitis.
- Alternative prophylactic treatments are sought to improve QOL outcomes.
Purpose of the Study:
- To compare QOL outcomes between conventional dissection tonsillectomy and azithromycin treatment for recurrent tonsillitis in children.
- To evaluate the long-term efficacy of azithromycin prophylaxis in managing recurrent tonsillitis.
Main Methods:
- A double-blind, randomized clinical trial involving 184 children with recurrent tonsillitis.
- Children were randomized into two groups: tonsillectomy (Group A) or weekly oral azithromycin (Group B).
- Dosage of azithromycin was weight-dependent (250 mg for ≤25 kg, 500 mg for ≥25 kg).
Main Results:
- No significant differences in ear, nose, and throat infections between groups over a 5-year follow-up.
- Both treatment groups showed improved QOL compared to pretreatment levels.
- QOL outcomes were similar between the tonsillectomy and azithromycin groups post-treatment.
Conclusions:
- Azithromycin serves as an effective prophylactic method against recurrent tonsillitis.
- Azithromycin treatment offers significant benefits for improving children's QOL.
- Azithromycin provides a viable alternative to surgery for managing recurrent tonsillitis and enhancing QOL.
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