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Infectious arthritis caused by Propionibacterium acnes: a report of two cases

M F Kooijmans-Coutinho1, H M Markusse, B A Dijkmans

  • 1Department of Rheumatology, University Hospital, Leiden, The Netherlands.

Insights

Propionibacterium acnes (P acnes) can cause infectious arthritis in native joints, even with sterile procedures. Clinicians should consider P acnes in synovial fluid as a potential pathogen, not just a contaminant.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Rheumatology

Background:

  • Propionibacterium acnes (P acnes) is a bacterium with low pathogenicity.
  • P acnes rarely causes arthritis in native joints, typically occurring in prosthetic joints.

Observation:

  • Two cases of infectious arthritis caused by P acnes in native joints are presented.
  • Infection likely resulted from direct microbial inoculation during arthrocentesis, despite aseptic techniques.

Findings:

  • P acnes was isolated from synovial fluid in both patients.
  • The clinical presentation and diagnostic challenges of P acnes infectious arthritis are highlighted.

Implications:

  • P acnes in synovial fluid should not be dismissed as a contaminant without careful clinical evaluation.
  • This underscores the importance of considering less common pathogens in joint infections.

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